Liverpool need at least a point to stay ahead of Manchester City, and a loss will mean they’ll remain second as City’s goal difference is too big.
Manchester United have named Romelu Lukaku in the starting lineup, and Marcus Rashford plays on the wing that sees Anthony Martial miss out. The Frenchman has an injury.
Paul Pogba, the man in form in midfield, will start in an attacking midfield role, while Scott McTominay and Ander Herrera will play in the central midfield role and protect the defence.
McTominay’s inclusion in place of Matic isn’t a surprise as the Serbian is out injured.
The defence has performed well of late, and the duo of Chris Smalling and Victor Lindelof start at the heart of the defence.
Additionally, the Red Devils have Jesse Lingard on the bench, and the England international might get a few minutes in the second half.
Confirmed Manchester United Lineup: De Gea, Young, Smalling, Lindelof, Shaw, Herrera, McTominay, Pogba, Lukaku, Rashford, Mata
Liverpool have gone with the usual front three of Sadio Mane, Roberto Firmino, and Mohamed Salah.
The big change is Trent Alexander-Arnold is on the bench as Jurgen Klopp has preferred James Milner in the right-back position.
Vigil van Dijk returns to the starting lineup after missing the clash against Bayern Munich due to a suspension. Wijnaldum, Fabinho, and Henderson start in midfield as Klopp has gone for the extra protection rather than Naby Keita who is a more attack-minded player.
Liverpool have Keita, Xherdan Shaqiri, and Daniel Sturridge to call upon from the bench if needed.
Confirmed Liverpool Lineup: Alisson, Milner, Van Dijk, Matip, Robertson, Wijnaldum, Henderson, Fabinho, Mane, Salah, Firmino